2-Methyl-2-propanyl 3-(aminomethyl)-1-azetidinecarboxylate
1-Boc-3-(aminomethyl)azetidine
CAS: 325775-44-8
Molecular Formula: C9H18N2O2
2-Methyl-2-propanyl 3-(aminomethyl)-1-azetidinecarboxylate - Names and Identifiers
2-Methyl-2-propanyl 3-(aminomethyl)-1-azetidinecarboxylate - Physico-chemical Properties
| Molecular Formula | C9H18N2O2 |
| Molar Mass | 186.25 |
| Density | 1.0234 g/mL at 25 °C |
| Boling Point | 260.6±13.0 °C(Predicted) |
| Flash Point | >110 °C |
| Vapor Presure | 0.012mmHg at 25°C |
| Appearance | Colorless Liquid |
| pKa | 9.97±0.29(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Sensitive | Air Sensitive |
| Refractive Index | 1.4670 |
| MDL | MFCD01861762 |
2-Methyl-2-propanyl 3-(aminomethyl)-1-azetidinecarboxylate - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R25 - Toxic if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 2810 |
| WGK Germany | 1 |
| Hazard Class | IRRITANT |
| Packing Group | Ⅲ |
2-Methyl-2-propanyl 3-(aminomethyl)-1-azetidinecarboxylate - Introduction
1-Boc-3-(aminomethyl)azetidine is an organic compound with the chemical formula C12H23NO3. It is a compound containing an aminomethyl group and an azetidine ring.
Nature:
1-Boc-3-(aminomethyl)azetidine is a solid with a white or white-like appearance. It is insoluble in water at normal temperature, but soluble in organic solvents such as alcohol, methanol and dimethyl sulfoxide.
Use:
1-Boc-3-(aminomethyl)azetidine is an important intermediate in organic synthesis. It is widely used for Amine protecting groups in organic synthesis. By introducing a Boc protecting group, the reactivity of the amine group can be protected and more selectivity can be provided in the synthesis.
Method:
1-Boc-3-(aminomethyl)azetidine can be prepared by reacting azetidine with tert-butoxycarbonyl chloride. First, azetidine is dissolved in an organic solvent, and then tert-butoxycarbonyl is slowly added to the reaction system. After the reaction, the product is purified by crystallization or column chromatography.
Safety Information:
1-Boc-3-(aminomethyl)azetidine is safe, but it is a chemical and should follow safe operating procedures and wear appropriate protective equipment when operating, such as gloves and goggles. At the same time, store it in a cool, dry and well-ventilated place, away from fire and combustibles. When using or disposing, comply with the relevant local regulations and handle in accordance with the correct method. In the event of an accident or discomfort, the application should be stopped immediately and medical assistance should be sought.
Nature:
1-Boc-3-(aminomethyl)azetidine is a solid with a white or white-like appearance. It is insoluble in water at normal temperature, but soluble in organic solvents such as alcohol, methanol and dimethyl sulfoxide.
Use:
1-Boc-3-(aminomethyl)azetidine is an important intermediate in organic synthesis. It is widely used for Amine protecting groups in organic synthesis. By introducing a Boc protecting group, the reactivity of the amine group can be protected and more selectivity can be provided in the synthesis.
Method:
1-Boc-3-(aminomethyl)azetidine can be prepared by reacting azetidine with tert-butoxycarbonyl chloride. First, azetidine is dissolved in an organic solvent, and then tert-butoxycarbonyl is slowly added to the reaction system. After the reaction, the product is purified by crystallization or column chromatography.
Safety Information:
1-Boc-3-(aminomethyl)azetidine is safe, but it is a chemical and should follow safe operating procedures and wear appropriate protective equipment when operating, such as gloves and goggles. At the same time, store it in a cool, dry and well-ventilated place, away from fire and combustibles. When using or disposing, comply with the relevant local regulations and handle in accordance with the correct method. In the event of an accident or discomfort, the application should be stopped immediately and medical assistance should be sought.
Last Update：2024-04-10 22:29:15
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Product Name: 1-Boc-3-(Aminomethyl)Azetidine Visit Supplier Webpage Request for quotation
CAS: 325775-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 325775-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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